Head movements evoked by electrical stimulation in the frontal eye field of the monkey: Evidence for independent eye and head control
Head movements evoked by electrical stimulation in the frontal eye field of the monkey: Evidence for independent eye and head control
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DOI：
10.1152/jn.01320.2005
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发表时间：
2006-06-01
影响因子：
2.5
通讯作者：
Chen, LLT
中科院分区：
文献类型：
--
作者：
Chen, LLT
当头部自由移动时，额眼场（FEF）中的电刺激引起眼睛和头部运动。然而，目前尚不清楚FEF刺激诱发的头部运动是否有助于转移视线，如视觉引导的协调眼-头凝视转移。在这里，我们研究了这个问题，系统地改变初始眼（IEP）和头部（IHP）的位置在刺激开始。尽管IEP和IHP以及刺激诱发的注视幅度的程度存在很大的变异性，但注视位移完全由眼睛（头部）位移引起。总体而言，大多数（3/4）刺激诱发的凝视转移由单独的眼睛运动组成，其中头部运动低于检测阈值。当头部运动确实发生时，它们通常开始较晚（重新凝视转移开始），并且与快速的眼睛减速相一致，导致随后的凝视幅度变化不大。这些头部运动往往达到他们的峰值速度超过100毫秒后，结束的凝视转移，表明头部速度分布是暂时分离的凝视驱动。有趣的是，在没有注视转移的情况下，FEF刺激有时会诱发头部运动，特别是当刺激开始时IEP偏离对侧（相对于刺激侧）时。此外，由FEF刺激引起的头部运动类似于在视觉引导的注视转移期间发生的头部运动的子集。这些独特的头部运动最大限度地减少了眼睛偏离轨道中心的情况，对视线转移的贡献很小。结果表明，头部运动控制可能是独立的眼睛控制的FEF。
When the head is free to move, electrical stimulation in the frontal eye field (FEF) evokes eye and head movements. However, it is unclear whether FEF stimulation-evoked head movements contribute to shifting the line of sight, like visually guided coordinated eye-head gaze shifts. Here we investigated this issue by systematically varying initial eye (IEP) and head (IHP) positions at stimulation onset. Despite the large variability of IEP and IHP and the extent of stimulation-evoked gaze amplitudes, gaze displacement was entirely accounted for by eye ( re head) displacement. Overall, the majority (3/4) of stimulation-evoked gaze shifts consisted of eye-alone movements, in which head movements were below the detection threshold. When head movements did occur, they often started late ( re gaze shift onset) and coincided with rapid eye deceleration, resulting in little change in the ensuing gaze amplitudes. These head movements often reached their peak velocities over 100 ms after the end of gaze shifts, indicating that the head velocity profile was temporally dissociated from the gaze drive. Interestingly, head movements were sometimes evoked by FEF stimulation in the absence of gaze shifts, particularly when IEP was deviated contralaterally (re the stimulated side) at stimulation onset. Furthermore, head movements evoked by FEF stimulation resembled a subset of head movements occurring during visually guided gaze shifts. These unique head movements minimized the eye deviation from the center of the orbit and contributed little to gaze shifts. The results suggest that head motor control may be independent from eye control in the FEF.