3-DIMENSIONAL COLLAGEN ARCHITECTURE IN BOVINE ARTICULAR-CARTILAGE
3-DIMENSIONAL COLLAGEN ARCHITECTURE IN BOVINE ARTICULAR-CARTILAGE
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DOI：
10.1302/0301-620x.73b5.1894669
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发表时间：
1991-09-01
影响因子：
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通讯作者：
BENTLEY, G
中科院分区：
文献类型：
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作者：
JEFFERY, AK;BLUNN, GW;BENTLEY, G
本文用扫描电镜观察了牛关节软骨胶原的三维结构及其与断裂线的关系，在中、浅层，胶原呈层状或叶状结构。 中间区的方向是垂直的，在浅表区弯曲成水平并平行于关节面。 每片叶子都由胶原纤维的精细网络组成。 相邻的叶片合并或紧密相连的桥接纤维和安排根据分裂线模式。 表面层（椎板）在形态上是不同的。虽然有序，但整体胶原结构在每个平面上是不同的（各向异性），这是以前的形态学和生物物理学研究中描述的特性。 由于关节软骨基质的所有成分密切相互作用，因此在考虑软骨功能和软骨生长、损伤和修复过程时，胶原蛋白的三维组织非常重要。
The three-dimensional architecture of bovine articular cartilage collagen and its relationship to split lines has been studied with scanning electron microscopy.In the middle and superficial zones, collagen was organised in a layered or leaf-like manner. The orientation was vertical in the intermediate zone, curving to become horizontal and parallel to the articular surface in the superficial zone. Each leaf consisted of a fine network of collagen fibrils. Adjacent leaves merged or were closely linked by bridging fibrils and were arranged according to the split-line pattern. The surface layer (lamina splendens) was morphologically distinct.Although ordered, the overall collagen structure was different in each plane (anisotropic) a property described in previous morphological and biophysical studies. As all components of the articular cartilage matrix interact closely, the three-dimensional organisation of collagen is important when considering cartilage function and the processes of cartilage growth, injury and repair.