Transplantation experiments on developing teleosts (Fundulus and perca)
Transplantation experiments on developing teleosts (Fundulus and perca)
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DOI：
10.1002/jez.1400720304
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发表时间：
1936-02-01
影响因子：
--
通讯作者：
Oppenheimer, JM
中科院分区：
文献类型：
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作者：
Oppenheimer, JM
在硬骨鱼类中，当将囊胚的背唇移植到年轻的原肠胚时，诱导胚胎形成。胚盾诱导形成的结构的性质取决于盾细胞的反应，胚外上皮诱导形成的结构的性质取决于背侧唇移植物的自分化。通过诱导和反应细胞控制分化的事实可以分别通过实验证明。在不同的条件下进行表明这两个过程都涉及正常的胚胎形成。然而，分化并不仅仅由这些相互作用控制。当植入卵黄囊上皮时，屏蔽材料可以分化出更多类型的结构，而不是相同的细胞在没有被移除的情况下产生的结构;因此，周围细胞施加的抑制在限制任何特定细胞群能够分化的结构类型方面是重要的。当移植到新的盾位置时，来自背唇或胚盾中其他地方的材料在某些情况下保留了它们自己的特征，但在其他情况下转化为结构，其性质受它们在宿主中的位置的影响。背唇移植物的自分化可以被宿主抑制，这一事实进一步证明了诱导系统和应答系统之间的相互作用。
In teleosts the dorsal lip of the blastopore, when transplanted to young gastrulae, induces embryo formation. The nature of structures induced from the embryonic shield is determined by the reactions of the responding shield cells, that of structures induced from the extra-embryonic epithelium is governed by self-differentiation of the dorsal lip graft. The fact that control of differentiation by inducing and reacting cells can be demonstrated separately by exps. performed under different conditions signifies that both processes are involved in normal embryo-formation. Differentiation is controlled, however, not by these interactions alone. Shield material when implanted on the yolk-sac epithelium can differentiate more types of structure than the same cells would have produced had they not been removed; thus inhibitions imposed by surrounding cells are important in limiting the types of structure which any particular group of cells is able to differentiate. Materials from the dorsal lip or elsewhere in the embryonic-shield when transplanted to new shield locations in some cases preserve their own character, but in others are transformed to structures the nature of which is influenced by their location in the host. The fact that self-differentiation of dorsal lip grafts can be suppressed by the host gives further evidence of interaction between inducing and responding systems.