Evidence of rickettsial spotted fever and ehrlichial infections in a subtropical territory of Jujuy, Argentina
Evidence of rickettsial spotted fever and ehrlichial infections in a subtropical territory of Jujuy, Argentina
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DOI：
10.4269/ajtmh.1999.61.350
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发表时间：
1999-08-01
影响因子：
3.3
通讯作者：
Santos-Buch, CA
中科院分区：
文献类型：
--
作者：
Ripoll, CM;Remondegui, CE;Santos-Buch, CA
在1993年11月至1994年3月期间，在阿根廷胡胡伊省发现了6例急性发热性疾病伴发皮疹的儿童患者。组织的免疫组织化学染色证实斑点热群立克次体感染的病人致命的疾病，和测试的病人的血清从疾病的康复期通过使用间接免疫荧光试验（IFA）证明抗体反应斑点热群立克次体。在接近指示病例的16个家庭中进行了血清调查。在通过IFA评估的105名健康受试者中，19名（18%）显示出与立克次体或埃里希体反应的抗体：4名具有与立克次体反应的抗体，15名具有与查菲埃里希体反应的抗体，1名具有与伤寒杆菌反应的抗体。Ambylomma cajennense是R.在南美洲的立克次氏体，是从该地区的宠物和马收集的。这些结果首次记录了阿根廷的立克次体斑点热和埃立克体感染。
Between November 1993 and March 1994, a cluster 6 pediatric patients with acute febrile illnesses associated with rashes was identified in Jujuy Province, Argentina. Immunohistochemical staining of tissues confirmed spotted fever group rickettsial infection in a patient with fatal diseas, and testing of serum of a patient convalescing from the illness by using an indirect immunofluorescence assay (IFA) demonstrated antibodies reactive with spotted fever group rickettsiae. A serosurvey was conducted among 16 households in proximity to the index case. Of 105 healthy subjects evaluated by IFA, 19 (18%) demonstrated antibodies reactive with rickettsiae or ehrlichiae: 4 had antibodies reactive with Rickettsia rickettsii, 15 with Ehrlichia chaffeensis, and 1 with R, typhi. Ambylomma cajennense, a known vector of R. rickettsii in South America, was collected from pets and horses in the area. These results are the first to document rickettsial spotted fever and ehrlichial infections in Argentina.