INPOCKETINGS OF THE CELL-MEMBRANE (CAVEOLAE) IN THE RAT MYOCARDIUM
INPOCKETINGS OF THE CELL-MEMBRANE (CAVEOLAE) IN THE RAT MYOCARDIUM
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DOI：
10.1016/s0022-5320(78)90051-5
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发表时间：
1978-01-01
期刊：
影响因子：
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通讯作者：
GABELLA, G
中科院分区：
文献类型：
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作者：
GABELLA, G
电镜观察大鼠乳头肌心肌细胞表面膜，除T小管开口外，还可见许多小囊泡。有些小泡是瓶状的，但许多其他的小泡是复合形状和大小不均匀的；它们都通过一个狭窄的颈部进入细胞间隙。其包装密度为6.1/.mu。M2为细胞表面；它们增加了约27%的细胞膜面积。肌浆网小管网络靠近小泡。膜内颗粒直径为9 nm，在小泡膜内的颗粒比表面膜内的颗粒少，并且在小泡颈周围没有特殊的排列。内皮细胞的小泡更小，尺寸更均匀，堆积密度更大（67.5/.mu.m2）。血管平滑肌细胞的小泡大小均匀，排列成行，与肌浆网相连，在其颈部周围有特征性的膜内颗粒分布。
The surface membrane of cardiac muscle cells of the rat papillary muscle shows on EM study, in addition to the openings of the T tubules, many small inpocketings (caveolae). Some caveolae are flask-shaped, but many others are composite in shape and nonuniform in size; they all open into the intercellular space through a single, narrow neck. Their packing density is 6.1/.mu.m2 of cell surface; they increase the cell membrane area by about 27%. A network of sarcoplasmic reticulum tubules lies close to the caveolae. Intramembranous particles, 9 nm in diameter, are fewer in the membrane of the caveolae than in the surface membrane proper and have no special arrangement around the caveolar necks. The caveolae of endothelial cells are smaller and uniform in size, and have a greater packing density (67.5/.mu.m2). The caveolae of vascular smooth muscle cells are small and uniform in size, are arranged in rows, are associated with sarcoplasmic reticulum and have a characteristic distribution of intramembranous particles around their necks.