Feeder vessel photocoagulation of subfoveal choroidal neovascularization secondary to age-related macular degeneration
Feeder vessel photocoagulation of subfoveal choroidal neovascularization secondary to age-related macular degeneration
复制标题
DOI：
10.1016/s0161-6420(98)94021-0
复制
发表时间：
1998-04-01
期刊：
影响因子：
13.7
通讯作者：
Matsuo, N
中科院分区：
文献类型：
--
作者：
Shiraga, F;Ojima, Y;Matsuo, N
目的：本研究旨在评估的可行性，激光光凝的供血血管的中心凹下脉络膜新生血管（CNV）继发于年龄相关性黄斑变性。患者和方法：连续170例中心凹下CNV继发于年龄相关性黄斑变性，供血血管检测37例吲哚菁绿色血管造影术，使用扫描激光检眼镜。染料激光光凝应用于中心凹外的供血血管，与中心凹spared.Results：26（70%），这37例患者的渗出表现完全解决。11例（30%）因复发或持续性CNV而表现持续或加重，25例（68%）视力提高或稳定。10例患者（27%）的最终视力为20/40或更好，6例患者（16%）的最终视力为20/50至20/100。预测视力结果为20/100或更好的重要因素是小CNV（2个椎间盘区域或更小，Fisher精确概率检验，P = 0.041），新生血管膜中无白色纤维组织（Fisher精确概率检验，P = 0.003），激光灼伤距离中心凹无血管区中心的最近距离（Fisher精确概率检验，P = 0.049）。术前视力与术后视力呈显著正相关（斯皮尔曼秩相关检验，P = 0.0076）。结论：对于继发于老年性黄斑变性的黄斑中心凹下CNV，应考虑采用供血血管光凝术，因为没有其他治疗方法具有更好的视力结果。
Purpose: This study aimed to assess the feasibility of laser photocoagulation of feeder vessels of subfoveal choroidal neovascularization (CNV) secondary to age-related macular degeneration.Patients and Methods: Of 170 consecutive patients with subfoveal CNV secondary to age-related macular degeneration, feeder vessels were detected in 37 patients by means of indocyanine green videoangiography using a scanning laser ophthalmoscope. Dye laser photocoagulation was applied to extrafoveal feeder vessels, with the fovea spared.Results: Twenty-six (70%) of those 37 patients had complete resolution of exudative manifestations. Persistent or worsened manifestations were seen in 11 patients (30%) because of recurrent CNV or persistent CNV, The visual acuity improved or stabilized in 25 patients (68%). Ten patients (27%) had a final visual acuity of 20/40 or better and six patients (16%) had a final visual acuity of 20/50 to 20/100. Significant factors prognostic of the visual outcome of 20/100 or better were small CNV (2 disc areas or smaller, Fisher's exact probability test, P = 0.041), the absence of white, fibrous tissue in neovascular membranes (Fisher's exact probability test, P = 0.003), and the closest distance of laser burns to the center of the foveal avascular zone (Fisher's exact probability test, P = 0.049). Preoperative visual acuity had a significant positive correlation with final visual acuity (Spearman's rank correlation test, P = 0.0076).Conclusion: Feeder vessel photocoagulation should be considered as a treatment option for subfoveal CNV secondary to age-related macular degeneration, because no other treatment method has a better visual outcome.