DENTAL HEALTH INDICES OF LONG-TERM CHILDHOOD CANCER SURVIVORS WHO HAD ORAL SUPERVISION DURING TREATMENT: A Case-Control Study
DENTAL HEALTH INDICES OF LONG-TERM CHILDHOOD CANCER SURVIVORS WHO HAD ORAL SUPERVISION DURING TREATMENT: A Case-Control Study
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DOI：
10.1080/08880010802237849
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发表时间：
2008-01-01
影响因子：
1.7
通讯作者：
Sevinir, Betuel
中科院分区：
文献类型：
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作者：
Cubukcu, Cigdem Elbek;Sevinir, Betuel
这项病例对照研究的目的是比较一组儿童癌症长期幸存者与年龄和性别匹配的健康对照组的牙齿健康状况。选择了所有至少5年无进展和/或无疾病的儿童。计算恒牙列龋指数（DMF/T）和乳牙列龋指数（dmf/t）。过去的数据从医疗和牙科记录中收集，并由其中一位作者单独阅读。受试者在初次诊断时的平均年龄为4.3 ± 0.3岁（范围0.5-14岁）。从停止治疗到目前进行牙科检查的平均时间为5.0 ± 0.7年。与健康受试者相比，研究组具有显著性（p 0.05）（分别为2.1 +/- 0.6和1.6 +/- 0.2）。头颈部放疗的存在（r = 0.427，p <0.05），儿童接受化疗的月数（r = 0.413，p <0.01），氟凝胶治疗的次数（r = 0.361，p <0.05）和dmf/t值之间分别存在显著的正相关性。根据这项研究的结果，我们的单位现在认为，通过半年一次的牙科检查，为每一个孩子谁将或已经在儿科肿瘤科治疗是强制性的。重点应放在龋齿预防上，包括饮食咨询，口腔卫生，必要时应用氟化物。
The aim of this case-control study was to compare the dental health of a group of long-term survivors of childhood cancer with that of age- and gender-matched healthy controls. All children who had been progress- and/or disease-free for at least 5 years were selected. Caries indices for permanent dentition (DMF/T) and primary dentition (dmf/t) were calculated. Past data were collected from medical and dental records and read separately by one of the authors. The mean age of the subjects at the initial diagnosis of the disease was 4.3 +/- 0.3 yr ( range 0.5-14 yr). The mean time lapse from the cessation of the therapy to the present dental examination was 5.0 +/- 0.7 yr. The study group had significantly (p .05) compared to healthy subjects (2.1 +/- 0.6 and 1.6 +/- 0.2, respectively). There was a significant positive correlation between the presence of head and neck radiotherapy (r = 0.427, p < .05), the number of months the child had been on chemotherapy (r = 0.413, p < .01), the number of fluoride gel treatments (r = .361, p < .05), and dmf/t values, separately. Based on the results of this study, our Unit now considers a through semiannual dental examination for every child who will be or has been treated at Pediatric Oncology Department to be mandatory. The focus should be on caries prevention and include dietary counseling, oral hygiene, and fluoride applications if necessary.