Isolation of an enzyme from Streptococcus sanguis which specifically cleaves IgA.
Isolation of an enzyme from Streptococcus sanguis which specifically cleaves IgA.
复制标题
从血链球菌中分离出一种特异性裂解 IgA 的酶。
作者：
A. Plaut;R. Genco;T. Tomasi
IgA protease, a metal-dependent endopeptidase elaborated by bacteria normally found in the human oral cavity and intestinal tract, can be isolated in good yield from culture filtrates of Streptococcus sanguis. The enzyme has pronounced specificity for secretory and serum IgA, which it cleaves to form Fcα and Fabα fragments.
