Correlates of increased lean muscle mass in women with polycystic ovary syndrome
Correlates of increased lean muscle mass in women with polycystic ovary syndrome
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DOI：
10.1530/eje-09-0398
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发表时间：
2009-10-01
影响因子：
5.8
通讯作者：
Lobo, R. A.
中科院分区：
文献类型：
--
作者：
Carmina, E.;Guastella, E.;Lobo, R. A.
目的：肌肉质量在决定多囊卵巢综合征（PCOS）患者心血管和代谢风险中起重要作用。此外，是否瘦质量影响颈动脉内膜中层厚度（IMT）在PCOS还没有assessed.Design前瞻性investigation.Methods：95名妇女与PCOS的年龄和体重匹配90排卵对照。所有妇女都进行了双能X线骨密度测定。脂肪和骨量。和骨密度（BMD）。测定血清睾酮、性激素结合球蛋白、胰岛素、血糖和颈动脉IMT。结果：PCOS组腰围、胰岛素均高于对照组，而QUICKI则低于对照组（P
Objective: Muscle mass plays all important role in determining cardiovascular and metabolic risks in polycystic ovary syndrome (PCOS). In addition, whether lean Mass influences carotid intima-media thickness (IMT) in PCOS has not been assessed.Design Prospective investigation.Methods: Ninety-five women with PCOS were age- and weight-matched to 90 ovulatory controls. All women had dual X-ray absorptiometry for lean. fat and bone mass. and bone mass density (BMD). Serum testosterone, sex hormone-binding globulin, insulin, and glucose and carotid IMT were determined. Free androgen index (FAI) and insulin resistance (by QUICKI) were calculated.Results: In PCOS, waist circumference and insulin were higher and QUICKI lower than in controls (P