Multi-sweep 3-dimensional ultrasound is accurate for in vivo muscle volume quantification, expanding use to larger muscles.
Multi-sweep 3-dimensional ultrasound is accurate for in vivo muscle volume quantification, expanding use to larger muscles.
复制标题
多次扫描 3 维超声可准确量化体内肌肉体积，从而将用途扩展到更大的肌肉。
DOI：
10.1016/j.jbiomech.2023.111501
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发表时间：
2023
影响因子：
2.4
通讯作者：
Murray,WendyM
中科院分区：
文献类型：
--
作者：
Budzikowski,JorieD;Murray,WendyM
肌肉体积是分析肌腱三维结构的重要参数。三维超声（3DUS）能够很好地量化小肌肉中的肌肉体积;然而，当肌肉的横截面积大于超声换能器在沿其长度沿着的任何点处的视场时，需要多次扫描来重建肌肉解剖结构。在多次扫描之间报告了混淆图像配准错误。在这里，我们详细介绍了成像体模研究，用于（1）定义采集协议，减少肌肉变形引起的3D重建中的不对准，以及（2）当体模太大而无法通过单次探头扫描完全成像时，量化3DUS测量体积的准确性。最后，我们（3）通过使用3DUS和磁共振成像（MRI）比较肱二头肌的体积，确定我们的方案用于活体测量的可行性。体模研究表明，操作员意图在多次扫描中使用恒定压力，可有效缓解图像错位，产生最小体积误差（1.70 ± 1.30%）。在扫描之间故意施加不同的压力复制了先前观察到的不连续性，导致更大的误差（5.30 ± 0.94%）。基于这些发现，我们采用凝胶袋支架，并使用3DUS获取肱二头肌肌肉的活体图像，并将该体积与MRI进行比较。我们没有观察到错位误差，并且成像模式之间没有显著差异（-0.71 ± 5.03%），表明3DUS可以可靠地用于量化需要多次换能器扫描的较大肌肉的肌肉体积。
Muscle volume is an important parameter in analyzing three-dimensional structure of muscle–tendon units. Three-dimensional ultrasound (3DUS) enables excellent quantification of muscle volume in small muscles; however, when a muscle’s cross sectional area is larger than the field of view of the ultrasound transducer at any point along its length, more than one sweep is necessary to reconstruct muscle anatomy. Confounding image registration errors have been reported between multiple sweeps. Here, we detail imaging phantom studies used to (1) define an acquisition protocol that reduces misalignment in 3D reconstruction caused by muscle deformation, and (2) quantify accuracy of 3DUS for measures of volume when phantoms are too large to be fully imaged via a single transducer sweep. Finally, we (3) establish the feasibility of our protocol forin vivomeasures by comparing biceps brachii muscle volumes using 3DUS and magnetic resonance imaging (MRI). Phantom studies indicate operator intent to use constant pressure across multiple sweeps effectively mitigates image misalignment, yielding minimal volume error (1.70 ± 1.30%). Intentional application of different pressure between sweeps replicated discontinuity observed previously, leading to larger errors (5.30 ± 0.94%). Based on these findings, we adopted a gel bag standoff and acquiredin vivoimages of biceps brachii muscles using 3DUS and compared this volume to MRI. We did not observe misalignment errors and there were no significant differences between imaging modalities (-0.71 ± 5.03 %), indicating 3DUS can reliably be used to quantify muscle volume in larger muscles requiring multiple transducer sweeps.