Synthesis of fused oxabicyclic systems by metal-catalyzed intramolecular addition of 1,3-cycloalkyldiones to alkynes
Synthesis of fused oxabicyclic systems by metal-catalyzed intramolecular addition of 1,3-cycloalkyldiones to alkynes
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DOI：
10.1021/ol0345632
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发表时间：
2003-05-29
期刊：
影响因子：
5.2
通讯作者：
Mascareñas, JL
中科院分区：
文献类型：
--
作者：
Gulías, M;Rodríguez, JR;Mascareñas, JL
[图形]容易获得的4-炔丙基-1，3-环己二酮和环戊二酮可以通过在室温下与催化量的适当金属络合物简单搅拌而化学和区域选择性地环异构化为合成吸引人的稠合氧杂双环体系。
[GRAPHIC]Readily available 4-propargyl-1,3-cyclohexanediones and cyclopentanediones can be chemo- and regioselectively cycloisomerized to synthetically appealing fused oxabicyclic systems by simply stirring at room temperature with catalytic amounts of an appropriate metal complex.