Fibrocartilaginous mesenchymoma arising in the pubic bone: A case report

Fibrocartilaginous mesenchymoma arising in the pubic bone: A case report
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耻骨中发生的纤维软骨间叶瘤:一例报告

DOI:
10.1111/pin.12052
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发表时间:
2013
期刊:
影响因子:
2.2
通讯作者:
Iwamoto Y
Iwamoto Y
中科院分区:
医学4区
文献类型:
--
作者:
Takahashi Y;Oda Y;Yamamoto H;Ishii T;Setsu N;Endo M;Matsuda S; Iwamoto Y

文献摘要

相似文献

摘要骨纤维软骨间质瘤是一种罕见的肿瘤,自1984年以来仅报道21例。它通常发生在儿童和青少年的长骨,但在这种情况下,肿瘤出现在耻骨上。FCM的病理诊断具有挑战性,由于其局部侵袭性,治疗应广泛切除。组织学上,我们的肿瘤是由梭形细胞的小叶增生并列软骨组织,缺乏细胞学检查。在软骨结节的周围观察到软骨骨化,并识别出肥大的软骨细胞,使人联想到骺板。病灶内切除,然后用苯酚和乙醇烧灼代替通常的广泛切除。我们报告一例FCM出现在一个罕见的解剖部位,耻骨,成功地治疗病灶内切除。手术后一年,患者无疾病。
Fibrocartilaginous mesenchymoma (FCM) of the bone is a rare tumor, with only 21 reported cases since 1984. It usually occurs in the long bones of children and adolescents, but in this case, the tumor arose in the pubic bone. The pathological diagnosis of FCM can be challenging, and the treatment should be a wide resection because of its locally aggressive behavior. Histologically, our tumor was composed of a lobular proliferation of spindle cells juxtaposed to the cartilaginous tissue, lacking cytological atypia. Enchondral ossification was observed at the periphery of the cartilaginous nodules, and hypertrophic chondrocytes was recognized, reminiscent of an epiphyseal plate. Intralesional resection followed by phenol and ethanol cauterization was performed in place of the usual wide resection. We report a case of FCM arising in a rare anatomical site, the pubic bone, successfully treated by intralesional resection. One year after the surgery, the patient is free of disease.