Effects of decreasing sugar-sweetened beverage consumption on body weight in adolescents: A randomized, controlled pilot study
Effects of decreasing sugar-sweetened beverage consumption on body weight in adolescents: A randomized, controlled pilot study
复制标题
DOI：
10.1542/peds.2005-0983
复制
发表时间：
2006-03-01
期刊：
影响因子：
8
通讯作者：
Ludwig, DS
中科院分区：
文献类型：
--
作者：
Ebbeling, CB;Feldman, HA;Ludwig, DS
OBJECTIVE.含糖饮料（SSB）在促进肥胖方面的作用是有争议的。观察数据链接SSB消费与过度体重增加;然而，随机对照试验缺乏，有必要解决这一争论。我们进行了一项初步研究，以检查减少SSB消耗对体重的影响。我们将103名13至18岁的青少年随机分配到干预组和对照组。干预，25周的时间，主要依赖于无热量饮料的家庭交付，以取代SSB，从而减少消费。SSB消耗量的变化是主要的过程测量，体重指数（BMI）的变化是主要终点。所有随机分配的受试者均完成了研究。在干预组中，SSB的消耗量减少了82%，而在对照组中没有变化。经性别和年龄调整后，干预组的BMI变化为0.07 +/- 0.14 kg/m2（平均值+/- SE），对照组为0.21 +/- 0.15 kg/m2。净差异为-0.14 +/- 0.21 kg/m2，总体上并不显著。然而，基线BMI是一个显著的影响因素。在基线BMI三分位数上限的受试者中，干预组（-0.63 +/-0.23 kg/m2）和对照组（-0.12 +/-0.26 kg/m2）的BMI变化存在显著差异，净效应为-0.75 +/-0.34 kg/m2。体重变化和基线BMI之间的相互作用不归因于基线SSB的消耗。一个简单的环境干预几乎完全消除了SSB消费在一个不同的青少年群体。减少SSB摄入量对体重的有益影响随着基线体重的增加而增加，这为美国儿科学会限制SSB摄入量的指南提供了额外的支持。
OBJECTIVE. The role of sugar-sweetened beverages (SSBs) in promoting obesity is controversial. Observational data link SSB consumption with excessive weight gain; however, randomized, controlled trials are lacking and necessary to resolve the debate. We conducted a pilot study to examine the effect of decreasing SSB consumption on body weight.METHODS. We randomly assigned 103 adolescents aged 13 to 18 years who regularly consumed SSBs to intervention and control groups. The intervention, 25 weeks in duration, relied largely on home deliveries of noncaloric beverages to displace SSBs and thereby decrease consumption. Change in SSB consumption was the main process measure, and change in body mass index (BMI) was the primary end point.RESULTS. All of the randomly assigned subjects completed the study. Consumption of SSBs decreased by 82% in the intervention group and did not change in the control group. Change in BMI, adjusted for gender and age, was 0.07 +/- 0.14 kg/m(2) (mean +/- SE) for the intervention group and 0.21 +/- 0.15 kg/m(2) for the control group. The net difference, -0.14 +/- 0.21 kg/m(2), was not significant overall. However, baseline BMI was a significant effect modifier. Among the subjects in the upper baseline-BMI tertile, BMI change differed significantly between the intervention (- 0.63 +/- 0.23 kg/m(2)) and control (- 0.12 +/- 0.26 kg/m(2)) groups, a net effect of -0.75 +/- 0.34 kg/m(2). The interaction between weight change and baseline BMI was not attributable to baseline consumption of SSBs.CONCLUSIONS. A simple environmental intervention almost completely eliminated SSB consumption in a diverse group of adolescents. The beneficial effect on body weight of reducing SSB consumption increased with increasing baseline body weight, offering additional support for American Academy of Pediatrics guidelines to limit SSB consumption.