Does chronic cervical myelopathy affect respiratory function?
Does chronic cervical myelopathy affect respiratory function?
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DOI：
10.3171/spi.2004.1.2.0175
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发表时间：
2004-09-01
影响因子：
2.8
通讯作者：
Takaoka, K
中科院分区：
文献类型：
--
作者：
Toyoda, H;Nakamura, H;Takaoka, K
物体。虽然急性颈髓损伤常常会损害呼吸功能，但慢性脊髓型颈椎病(CCM)患者的呼吸功能改变却没有很好的文献记载。本研究旨在评价慢性阻塞性肺疾病患者的呼吸功能。对94例CCM患者在接受椎板扩大成形术前进行了肺活量测定。将这些测量结果与年龄和性别匹配的对照组无脊髓病患者的测量结果进行比较。研究患者还被分为两组：C3-4椎间盘水平以上或以下的脊柱受压病变患者的呼吸功能进行比较。CCM患者的肺活量值明显低于对照组。在脊髓受压程度高于C3-4的患者中，肺活量值低于受压水平低于C3-4的患者。CCM组的每分钟静息呼吸频率增加。CCM组最大呼气流速明显降低，50%和25%肺活量时呼气流速明显增加。结果表明，CCM患者的呼气流量可能受损或不完全。潜在的亚临床呼吸功能障碍似乎与CCM有关。
Object. Although respiratory function is often impaired by acute cervical spinal cord injury, changes in respiratory function in patients with chronic cervical myelopathy (CCM) are not well documented. The purpose of this study was to evaluate the respiratory function of patients with CCM.Methods. Spirometric parameters were measured in 94 patients with CCM before they underwent expansive laminoplasty. These measurements were compared with those obtained in age- and sex-matched control group patients without myelopathy. The study patients were also subdivided into two groups: those with spinal compressive lesions above, or below the C3-4 disc level were compared in terms of respiratory function.The vital capacity values measured in patients with CCM were significantly lower than those in the control group. In patients in whom spinal cord compression was present above C3-4, vital capacity values were lower than in patient, in whom the compression level was below C3-4. The resting respiratory rate per minute was elevated in the, CCM group. Peak expiratory flow rate was significantly decreased, and expiratory velocities at 50 and 25% of vital capacity were significantly increased in the CCM group.Conclusions. The results indicated that expiratory flow may be impaired or incomplete in patients with CCM. An underlying subclinical respiratory dysfunction appears to be associated with CCM.