Intranasal oxytocin enhances positive self-attribution in healthy men
Intranasal oxytocin enhances positive self-attribution in healthy men
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DOI：
10.1016/j.jpsychores.2014.06.016
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发表时间：
2014-11-01
影响因子：
4.7
通讯作者：
Heinrichs, Markus
中科院分区：
文献类型：
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作者：
Colonnello, Valentina;Heinrichs, Markus
目的：越来越多的研究一致表明，对他人的社会反应受到神经激素催产素的影响。然而，催产素在自我认知中的潜在作用仍未被探索。因此，我们研究了催产素是否会影响自我相关信息加工早期努力阶段的积极和消极形容词的自我归因。方法：在一项随机双盲研究中，60名健康男性参与者在完成一项分类任务之前，分别服用24 iu的催产素或安慰剂。在这项任务中，他们被要求尽快将积极和消极的形容词分类为自我或非自我类别。结果：与安慰剂相比，催产素治疗的参与者报告了对自己更积极的态度。结论：目前的研究结果表明，催产素会影响自我相关信息加工的早期阶段，并提示催产素系统可能参与以自我消极表征为特征的精神病理状况。(C) 2014 Elsevier Inc .版权所有
Objective: A growing body of studies consistently demonstrates that social responsiveness toward others is influenced by the neurohormone oxytocin. However, the potential role of oxytocin for self-perception remains relatively unexplored. Thus, we investigated whether oxytocin administration influences the self-attribution of positive and negative adjectives at the early, effortful stage of self-related information processing.Methods: Sixty healthy male participants received either 24 I.U. oxytocin or a placebo in a randomized double-blind study before completing a sorting task, in which they were instructed to co-classify, as fast as possible, positive and negative adjectives into either self or non-self categories.Results: Oxytocin-treated participants reported stronger positive attitudes toward themselves compared to placebo.Conclusions: The present findings demonstrate that oxytocin administration influences the early stage of self-related information processing and suggests that the oxytocinergic system might be involved in psychopathological conditions characterized by a negative representation of self. (C) 2014 Elsevier Inc All rights reserved.