Role of medial temporal lobe in extensive retrieval of task-related knowledge

Role of medial temporal lobe in extensive retrieval of task-related knowledge
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DOI:
10.1002/hipo.10027
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发表时间:
2002-01-01
期刊:
影响因子:
3.5
通讯作者:
Niki, K
Niki, K
中科院分区:
医学3区
文献类型:
--
作者:
Luo, J;Niki, K

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本研究采用三重语义判断任务考察了内侧颞叶在深层语义加工中的作用。通过改变与顶部词语义相关的底部词的数量,我们可以将重新激活“旧”语义关联的效果和建立“新”语义关联的效果在MTL上分离。事件相关功能磁共振成像分析结果表明,MTL在提取旧语义联想时比建立新语义联想时更活跃。MTL在语义判断任务中的功能被解释为辅助任务相关知识的广泛提取过程。(C)2002 Wiley-Liss,Inc.
The role of medial temporal lobe (MTL) in deep semantic processing was examined in a triple semantic judgment task in which subjects were asked to decide which one of the two bottom words was more semantically fit to the top word. By changing the number of bottom words that are semantically related to the top word, we can disassociate effects of reactivating the "old" semantic associations and effects of establishing "new" semantic associations on the MTL. The results of event-related fMRI analysis indicated that MTL was more activated in the retrieval of old semantic associations than in the establishment of new semantic associations. The function of MTL in this semantic judgment task was explained as subserving the process of extensive retrieval of task-related knowledge. (C) 2002 Wiley-Liss, Inc.