An exploration of the role of the superior temporal gyrus in visual search and spatial perception using TMS
An exploration of the role of the superior temporal gyrus in visual search and spatial perception using TMS
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DOI：
10.1093/brain/awh244
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发表时间：
2004-10-01
期刊：
影响因子：
14.5
通讯作者：
Milner, AD
中科院分区：
文献类型：
--
作者：
Ellison, A;Schindler, I;Milner, AD
这项研究试图调查最近的索赔H.- O. Karnath和他的同事们认为，忽视患者神经系统损伤的关键部位位于右侧上级颞回（STG），而不是传统认为的右侧后顶叶皮层（PPC）。使用经颅磁刺激（TMS），我们首先测试了右STG参与一项通常用于诊断忽视的任务，即里程碑任务。没有证据表明，在处理这项任务的关键参与的权利STG，虽然证据被发现参与的权利PPC。然而，当我们考察TMS对探索性搜索的影响时，发现了右侧STG和右侧PPC之间的双重分离，当需要处理连接项时，发现了右侧PPC（而不是STG）的参与，这与我们以前的研究一致。然而，当需要对特征项进行困难的探索性搜索时，发现涉及正确的STG（而不是PPC）。一个迄今为止未知的作用，右STG在视觉搜索任务被发现。这些数据表明，有关导致忽视样症状的脑损伤区域的结论高度依赖于用于诊断它们的任务，右侧PPC中的病变导致地标任务和联合视觉搜索的缺陷，右侧STG中的病变导致基于特征的系列探索性搜索任务的缺陷。
This study sought to investigate the recent claim by H.-O. Karnath and his colleagues that the crucial locus of neurological damage in neglect patients lies in the right superior temporal gyrus (STG), and not in the right posterior parietal cortex (PPC) as conventionally thought. Using transcranial magnetic stimulation (TMS), we first tested the involvement of the right STG in a task commonly used in the diagnosis of neglect, the landmark task. No evidence was found for a critical involvement of the right STG in the processing of this task, though evidence was found for the involvement of the right PPC. In contrast, however, when we examined the effects of TMS on exploratory search, a double dissociation between right STG and right PPC was found. When the processing of conjunction items was required, involvement of the right PPC (and not STG) was found in accordance with our previous research. When a difficult exploratory search through feature items was required, however, the right STG (not PPC) was found to be involved. A hitherto unknown role for right STG in visual search tasks was thus uncovered. These data suggest that conclusions about the area of brain damage resulting in neglect-like symptoms are highly dependent on the task used to diagnose them, with lesions in right PPC leading to deficits on the landmark task and conjunction visual search, and lesions in right STG resulting in deficits in feature based serial exploratory search tasks.