SQUINT: a multiple alignment program and editor

SQUINT: a multiple alignment program and editor
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DOI:
10.1093/bioinformatics/btm128
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发表时间:
2007-06-15
期刊:
影响因子:
5.8
通讯作者:
Rodrigo, Allen G.
Rodrigo, Allen G.
中科院分区:
生物学3区
文献类型:
--
作者:
Goode, Matthew G.;Rodrigo, Allen G.

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SQUINT 是一种序列比对工具,它将自动渐进序列比对与手动编辑功能相结合。该程序以标准格式导入核苷酸或氨基酸序列多重比对文件,并允许用户同时查看同一多重比对的两个翻译。一个视图中的编辑会立即反映在另一个视图中,并且更改的评分成本会实时显示。使用各种比对参数的渐进多重比对可以对任何序列块进行,包括嵌入现有比对中的块。
SQUINT is a sequence alignment tool, and combines both automated progressive sequence alignment with facilities for manual editing. The program imports nucleotide or amino acid sequence multiple alignment files in standard formats, and permits users to view two translations of the same multiple alignment simultaneously. Edits in one view are instantaneously reflected in the other, and the scoring cost of the changes are shown in real-time. Progressive multiple alignments, using a variety of alignment parameters, can be performed on any block of sequences, including blocks embedded in the existing alignment.