Searching and Navigating UniProt Databases.
Searching and Navigating UniProt Databases.
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DOI：
10.1002/0471250953.bi0127s50
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发表时间：
2015-06-19
影响因子：
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通讯作者：
UniProt Consortium
中科院分区：
文献类型：
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作者：
Pundir S;Magrane M;Martin MJ;O'Donovan C;UniProt Consortium
通用蛋白质资源（UniProt）是蛋白质序列和注释数据的综合资源。UniProt网站每月约有400，000名独立访问者，是访问UniProt的主要途径。它提供了十个可搜索的数据集和三个主要工具。关键的UniProt数据集是UniProt知识库（UniProtKB）、UniProt参考聚类（UniRef）和UniProt档案（UniParc）以及完全测序基因组的蛋白质集（Proteomes）。其他支持数据集包括UniProtKB蛋白条目中存在的蛋白质信息，如文献引用，分类学，亚细胞位置等。本文重点介绍如何使用UniProt数据集。基本协议描述了UniProt数据集的导航和搜索机制，而两个替代协议建立在基本协议的基础上，以描述高级搜索和查询构建。
The Universal Protein Resource (UniProt) is a comprehensive resource for protein sequence and annotation data. The UniProt website receives approximately 400,000 unique visitors per month and is the primary means to access UniProt. It provides ten searchable datasets and three main tools. The key UniProt datasets are the UniProt Knowledgebase (UniProtKB), the UniProt Reference Clusters (UniRef) and the UniProt Archive (UniParc) and protein sets for completely sequenced genomes (Proteomes). Other supporting datasets include information about proteins that is present in UniProtKB protein entries like literature citations, taxonomy, subcellular locations, etc. This paper focuses on how to use UniProt datasets. The basic protocol describes navigation and searching mechanisms for the UniProt datasets while two alternative protocols build on the basic protocol to describe advanced search and query building.