PHYSICAL MODELS OF THE SMALLER PULMONARY AIRWAYS
PHYSICAL MODELS OF THE SMALLER PULMONARY AIRWAYS
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DOI：
10.1152/jappl.1992.72.6.2402
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发表时间：
1992-06-01
影响因子：
3.3
通讯作者：
OLSON, DE
中科院分区：
文献类型：
--
作者：
HAMMERSLEY, JR;OLSON, DE
任何内化流都表现出与其围合几何形状密切耦合的相互作用。因此，努力获得对体内气道运输现象的理解，要求仔细关注那些限制和改变区域空气运动的解剖气道特征。我们提出了一系列的人类小气道铸件的分析，以完善和扩展目前的小气道分岔的几何描述。气道形状因素被认为有一个高倾向，以改变该区域内气流的流体动力学是专门解决。这些解剖和流体分析的结果被用来发展两种平均对称和不对称的分岔模式。最后，提出了符合这些要求的物理分岔模型的生产方法，以在气道研究中开发解剖和流动相似性的合理表示。
Any internalized flow exhibits closely coupled interactions with its confining geometry. Efforts to gain an understanding of in vivo airway transport phenomena, therefore, dictate that careful attention be paid to those anatomic airway features that constrain and modify regional air movement. We present a series of analyses of human small airway casts to refine and extend the current geometric description of small airway bifurcations. Airway shape factors believed to have a high propensity to alter the fluid dynamics of airflows within this region are specifically addressed. The results of these anatomic and fluidic analyses are used to develop two average symmetrical and asymmetrical bifurcation patterns. Finally, methods for the production of physical bifurcation models conforming to these requirements are presented to develop a rational representation of anatomic as well as flow similitude during airway research.