Risk reduction through family therapy (RRFT): Protocol of a randomized controlled efficacy trial of an integrative treatment for co-occurring substance use problems and posttraumatic stress disorder symptoms in adolescents who have experienced interperson
Risk reduction through family therapy (RRFT): Protocol of a randomized controlled efficacy trial of an integrative treatment for co-occurring substance use problems and posttraumatic stress disorder symptoms in adolescents who have experienced interperson
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通过家庭治疗（RRFT）降低风险：针对经历过人际交往的青少年同时发生的物质使用问题和创伤后应激障碍症状进行综合治疗的随机对照疗效试验方案
DOI：
10.1016/j.cct.2020.106012
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发表时间：
2020
影响因子：
2.2
通讯作者：
Danielson,CarlaKmett
中科院分区：
文献类型：
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作者：
Hahn,AustinM;Adams,ZacharyW;Chapman,Jason;McCart,MichaelR;Sheidow,AshliJ;deArellano,MichaelA;Danielson,CarlaKmett
数十年的研究表明，童年时期接触创伤事件，特别是人际暴力经历（IPV；性虐待、身体虐待、目击暴力）会增加负面行为和情感结果的风险，包括药物使用问题 (SUP) 和创伤后应激障碍 (PTSD)。尽管这种明确的联系——包括对 SUP 和 PTSD 之间共同的病因学和功能联系的实证支持——该领域一直缺乏针对青少年群体的金标准治疗。为了解决这一差距，我们的团队最近完成了一项大型随机对照试验，以评估通过家庭治疗降低风险 (RRFT) 的功效，这是一种针对经历过 IPV 和其他创伤事件的青少年的基于暴露的综合风险降低和治疗方法。本文的目的是详细描述这项旨在减少 SUP、PTSD 症状和相关风险行为的随机对照试验的设计和方法，并测量从治疗前到进入后 18 个月的结果。具体来说，详细介绍了招募和抽样程序、评估措施和方法、干预措施的描述以及评估全方位结果的计划统计方法。还讨论了这项工作的临床和研究意义。
Decades of research demonstrate that childhood exposure to traumatic events, particularly interpersonal violence experiences (IPV; sexual abuse, physical abuse, witnessing violence), increases risk for negative behavioral and emotional outcomes, including substance use problems (SUP) and posttraumatic stress disorder (PTSD). Despite this well-established link—including empirical support for shared etiological and functional connections between SUP and PTSD –the field has been void of a gold standard treatment for adolescent populations. To address this gap, our team recently completed a large randomized controlled trial to evaluate the efficacy of Risk Reduction through Family Therapy (RRFT), an integrative and exposure-based risk-reduction and treatment approach for adolescents who have experienced IPV and other traumatic events. The purpose of this paper is to provide a detailed description of the design and methods of this RCT designed to reduce SUP, PTSD symptoms, and related risk behaviors, with outcomes measured from pre-treatment through 18 months post-entry. Specifically, the recruitment and sampling procedures, assessment measures and methods, description of the intervention, and planned statistical approaches to evaluating the full range of outcomes are detailed. Clinical and research implications of this work are also discussed.