Comparison of survival rates after bland arterial embolization and ablation versus surgical resection for treating solitary hepatocellular carcinoma up to 7 cm
Comparison of survival rates after bland arterial embolization and ablation versus surgical resection for treating solitary hepatocellular carcinoma up to 7 cm
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DOI：
10.1097/01.rvi.0000161377.33557.20
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发表时间：
2005-07-01
影响因子：
2.9
通讯作者：
Brown, KT
中科院分区：
文献类型：
--
作者：
Maluccio, M;Covey, AM;Brown, KT
目的：绝大多数肝细胞癌（HCC）发生在有潜在肝功能障碍的患者中，因此只有一小部分具有足够肝储备的患者可以进行手术切除。本研究分析了作者使用温和动脉栓塞联合射频消融 (RFA) 或经皮乙醇注射 (PEIT) 与手术切除治疗直径不超过 7 cm 的孤立性 HCC 的结果。 材料和方法：对 1996 年 1 月至 2002 年 8 月期间接受手术切除或温和栓塞联合局部消融治疗孤立性 HCC 的所有患者进行回顾性分析。采用Kaplan-Meier法计算无进展生存率和总生存率。结果：手术切除40例，栓塞消融33例。各组之间的年龄、性别和治疗病变的大小没有显着差异。栓塞/消融组有更多被分类为 Okuda 11 期的患者（P
PURPOSE: The vast majority of hepatocellular carcinomas (HCC) occur in patients with underlying liver dysfunction, making surgical resection available to only a subset of patients with adequate hepatic reserve. This study analyzes the authors' results with bland arterial embolization combined with radiofrequency ablation (RFA) or percutaneous ethanol injection (PEIT) compared with surgical resection for the treatment of solitary HCC up to 7 cm in size.MATERIALS AND METHODS: A retrospective review of all patients undergoing either surgical resection or bland embolization combined with local ablation for solitary HCC between January 1996 and August 2002 was performed. Progression-free survival rate and overall survival rate were calculated by the Kaplan-Meier method.RESULTS: There were 40 patients who underwent surgical resection and 33 patients who underwent embolization and ablation. Age, gender, and size of the treated lesion were not significantly different between the groups. The embolization/ablation group had more patients classified as Okuda stage 11 (P