Synthesis of Water-Soluble, Thiolate-Protected Gold Nanoparticles Uniform in Size
Synthesis of Water-Soluble, Thiolate-Protected Gold Nanoparticles Uniform in Size
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DOI：
10.1021/acs.nanolett.6b00981
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发表时间：
2016-05-01
期刊：
影响因子：
10.8
通讯作者：
Kornberg, Roger D.
中科院分区：
文献类型：
--
作者：
Azubel, Maia;Kornberg, Roger D.
通过对Brust等人的方法的修改，合成了尺寸均匀的水溶性、硫醇盐保护的金纳米颗粒，而不需要纯化。该方法的改进是在第一步中进行平衡，这被证明对于实现尺寸均匀性至关重要。硫醇与金的比例控制颗粒的尺寸，硫醇的选择控制颗粒对硫醇交换的反应性。
By a modification of the method of Brust et al., water-soluble, thiolate-protected gold nanoparticles that are uniform in size were synthesized with no requirement for purification. The modification of the method was equilibration in the first step, which proved crucial for achieving size homogeneity. The thiol-to-gold ratio controlled the size of the particles, and the choice of thiol controlled the reactivity of the particles toward thiol exchange.