Synthesis, characterization and biological evaluation of strontium/magnesium-co-substituted hydroxyapatite
Synthesis, characterization and biological evaluation of strontium/magnesium-co-substituted hydroxyapatite
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锶/镁共取代羟基磷灰石的合成、表征及生物学评价
DOI：
10.1177/0885328216633892
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发表时间：
2016-07-01
影响因子：
2.9
通讯作者：
Yang, Xianjin
中科院分区：
文献类型：
--
作者：
Geng, Zhen;Wang, Renfeng;Yang, Xianjin
本研究旨在研究两种重要的生物阳离子Mg 2+和Sr 2+共同取代到羟基磷灰石（Ca-10（PO 4）（6）（OH）（2），HA）结构中的贡献。通过水热法合成了取代的样品，所述水热法涉及添加含Mg 2+和Sr 2+的前体以部分取代磷灰石结构中的Ca 2+。研究了4种不同Mg ~（2+）和Sr ~（2+）浓度（（Mg+Sr）/（Mg+Sr+Ca）=30%）的共取代HA样品，并与纯HA进行了比较。实验结果表明，只有少量的Mg（Mg/（Mg+Ca+Sr））
The present study aims to investigate the contribution of two biologically important cations, Mg2+ and Sr2+, when co-substituted into the structure of hydroxyapatite (Ca-10(PO4)(6)(OH)(2), HA). The substituted samples were synthesized by a hydrothermal method that involved the addition of Mg2+ and Sr2+ containing precursors to partially replace Ca2+ in the apatite structure. Four co-substituted HA samples with different concentrations of Mg2+ and Sr2+ ((Mg+Sr)/(Mg+Sr+Ca)=30%) were investigated, and they were compared with pure HA. Experimental results showed that only a limited amount of Mg (Mg/(Mg+Ca+Sr)