Linear performance characteristics of latissimus dorsi muscle: potential for cardiac assistance.
Linear performance characteristics of latissimus dorsi muscle: potential for cardiac assistance.
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背阔肌的线性性能特征：心脏辅助的潜力。
DOI：
10.1097/01.mat.0000084103.26533.19
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发表时间：
2003
期刊：
影响因子：
--
通讯作者：
Sweeney,JamesD
中科院分区：
文献类型：
--
作者：
Gustafson,KennethJ;Guilbeau,EricJ;Sweeney,JamesD
Knowledge of the quantitative performance capabilities of skeletal muscle in a linear geometry is necessary to predict the performance and to optimize the design of linearly configured, skeletal muscle powered cardiac assist devices (MCADs). This study determined the performance characteristics of goat latissimus dorsi muscle (LDM) using a linear, exvivo experimental apparatus. In five goats, the LDM (130.6±18.8 g) was dissected free of its distal attachments, connected to a series of weights (500 to 2250 g), and maximal tetanic contractions were elicited via thoracodorsal nerve stimulation. Second order polynomial equations were derived to represent each of the following variables versus load: muscle prestretch (range 1.5 to 5.4 cm), contraction duration (220 to 360 milliseconds), contraction shortening distance (13.5 to 10.9 cm), contraction velocity (60 to 31 cm/s), generated stroke power (3 to 7 W), and stroke work (0.7 to 2.4 J). Analysis of the potential stroke volumes obtained with a linearly configured, cylindrically shaped MCAD directly coupled to the circulation indicate that a feasible MCAD operating region exists based on the LDM performance data across a range of device geometries and mean ejection pressures.
