Elevated C-Reactive Protein and Hypoalbuminemia Measured before Resection of Colorectal Liver Metastases Predict Postoperative Survival

Elevated C-Reactive Protein and Hypoalbuminemia Measured before Resection of Colorectal Liver Metastases Predict Postoperative Survival
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DOI:
10.1159/000280021
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发表时间:
2010-01-01
期刊:
影响因子:
2.7
通讯作者:
Morita, Koji
Morita, Koji
中科院分区:
医学3区
文献类型:
--
作者:
Kobayashi, Takashi;Teruya, Masanori;Morita, Koji

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背景:很少有研究调查格拉斯哥预后评分(GPS)(结直肠肝转移切除术(CRLM)之前测量的基于炎症的预后评分)是否可以预测术后生存。患者和方法:对 63 名连续接受 CRLM 根治性切除的患者进行了调查。 GPS 根据入院数据计算如下:同时患有 C 反应蛋白升高 (>10 mg/l) 和低白蛋白血症 (= 3(相对风险 2.83)和 GPS1/2(相对风险 3.07)的患者。结论:术前测量的 GPS 和肝转移数量可作为接受 CRLM 根治性切除的患者术后结果的新预测指标。版权所有 (C) 2010 S. Karger股份公司,巴塞尔
Background: Few studies have investigated whether the Glasgow Prognostic Score (GPS), an inflammation-based prognostic score measured before resection of colorectal liver metastasis (CRLM), can predict postoperative survival. Patients and Methods: Sixty-three consecutive patients who underwent curative resection for CRLM were investigated. GPS was calculated on the basis of admission data as follows: patients with both an elevated C-reactive protein (>10 mg/l) and hypoalbuminemia (= 3 (relative risk 2.83) and GPS1/2 (relative risk 3.07). Conclusions: GPS measured before operation and the number of liver metastases may be used as novel predictors of postoperative outcomes in patients who underwent curative resection for CRLM. Copyright (C) 2010 S. Karger AG, Basel