The link between the use of crack cocaine and the sexually transmitted diseases of a clinic population - A comparison of adolescents with adults
The link between the use of crack cocaine and the sexually transmitted diseases of a clinic population - A comparison of adolescents with adults
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DOI：
10.1097/00007435-199611000-00013
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发表时间：
1996-11-01
影响因子：
3.1
通讯作者：
Fichtner, R
中科院分区：
文献类型：
--
作者：
Ellen, JM;Langer, LM;Fichtner, R
背景和目的：确定个人和/或伴侣使用强效可卡因是否与早期梅毒或淋病的诊断无关，与高危性行为无关，并确定强效可卡因与相关的性传播疾病(STDS)在青少年和成年人中的关系是否相似。研究设计：对三个城市就诊的异性恋男性和女性进行横断面行为调查。结果：多因素分析显示，性行为前或性行为中吸食强效可卡因等毒品的男性更容易被诊断为梅毒(优势比[OR]=1.49；可信区间[CI]=1.06，2.13)。被诊断为淋病的男性年龄较小(OR=0.94；CI=0.92，0.96)，与可卡因吸毒者发生性关系(OR=1.99；CI=1.36，2.91)，上次与非主要性伴侣发生性关系时未使用安全套(OR=1.59；CI=1.09，2.13)，未与静脉吸毒者发生性关系(OR=0.45；CI=0.22，0.95)。女性患梅毒无独立危险因素，但年龄较小是淋病的独立危险因素(OR=0.95；CI=0.91，0.99)。男性强效可卡因和梅毒与淋病、女性强效可卡因和梅毒的相关性不显著。结论：本研究结果突出了淋病和梅毒高危人群与成人和青少年强效可卡因相关行为的差异。这些差异的性质支持对每种性传播疾病以及青少年和成人使用不同的干预策略。
Background and Objectives: To determine whether personal and/or a partner's use of crack cocaine is associated with the diagnosis of early syphilis or gonorrhea independent of high-risk sex behaviors, and to determine whether the relationships between crack cocaine and associated sexually transmitted diseases (STDs) are similar for adolescents and adults.Study Design: A cross-sectional behavioral survey of heterosexual males and females attending public STD clinics in three cities. Logistic regression was used to identify risk behavior patterns associated with each STD compared with no STD.Results: Multivariate analysis revealed that men who were high on drugs, including crack cocaine, before or during sex were more likely to be diagnosed with syphilis (Odds Ratio [OR] = 1.49; Confidence Intervals [CI] = 1.06, 2.13). Males more likely to be diagnosed with gonorrhea were younger (OR = 0.94; CI = 0.92, 0.96), had sex with a crack cocaine user (OR = 1.99; CI = 1.36, 2.91), did not use condoms last time they had sex with a nonmain partner (OR = 1.59; CI = 1.09, 2.13), and did not have sex with an intravenous drug user (OR = 0.45; CI = 0.22, 0.95). For women, there were no independent risk factor for syphilis but younger age was a risk factor for gonorrhea (OR = 0.95; CI = 0.91, 0.99). The associations between crack cocaine and syphilis and gonorrhea in men and between crack cocaine and syphilis in women were not significant among adolescents in this study.Conclusion: The results of this study highlight the differences in the crack cocaine-related behaviors of adults and adolescents at risk for gonorrhea and syphilis. The nature of these differences support the use of distinct intervention strategies for each STD and for adolescents and adults.