ETHANOL EFFECTS ON AGGRESSION OF RATS SELECTED FOR DIFFERENT LEVELS OF AGGRESSIVENESS
ETHANOL EFFECTS ON AGGRESSION OF RATS SELECTED FOR DIFFERENT LEVELS OF AGGRESSIVENESS
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DOI：
10.1016/0091-3057(87)90187-0
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发表时间：
1987-08-01
影响因子：
3.6
通讯作者：
HALL, J
中科院分区：
文献类型：
--
作者：
BLANCHARD, RJ;HORI, K;HALL, J
面对陌生的雄性入侵者的雄性老鼠被分为无攻击性、低至中等攻击性和高度攻击性三组。在低剂量（0.3和0.6 g/kg）乙醇的试验中，非攻击性大鼠没有变得具有攻击性；中低水平动物的攻击行为频率和持续时间显著增加；但具有高度攻击性的老鼠表现出轻微的（不显著的）下降。较高的乙醇剂量（1.2 g/kg）始终导致攻击性降低。这种低剂量乙醇增强攻击的速率依赖性与下述观点是一致的：这种增强的机制涉及乙醇干扰某些通常起限制或抑制攻击作用的机制。
Male rats confronting strange male intruders into their home cages were divided into nonaggressive, low-to-intermediate aggressive, and highly aggressive groups. In tests with low (0.3 and 0.6 g/kg) doses of ethanol the nonaggressive rats did not become aggressive; low-intermediate animals showed a significant increase in frequency and duration of attack behaviors; but highly aggressive rats displayed a slight (nonsignificant) decline. A higher ethanol dose (1.2 g/kg) consistently led to decreased aggression. This rate-dependency of the enhancement of aggression by low doses of ethanol is concordant with a view that the mechanism of this enhancement involves ethanol interference with some mechanism which normally acts to limit or inhibit attack.