WEB Intrasaccular Flow Disruptor-Prospective, Multicenter Experience in 83 Patients with 85 Aneurysms
WEB Intrasaccular Flow Disruptor-Prospective, Multicenter Experience in 83 Patients with 85 Aneurysms
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DOI：
10.3174/ajnr.a4028
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发表时间：
2014-11-01
影响因子：
3.5
通讯作者：
Pierot, L.
中科院分区：
文献类型：
--
作者：
Papagiannaki, C.;Spelle, L.;Pierot, L.
背景和目的：在小型回顾性系列研究中分析了WEB血流阻断的安全性和有效性。本研究的目的是评估一个大的，多中心的，前瞻性收集population.MATERIALS和方法的安全性和有效性的WEB流量中断：从2011年6月至2013年10月在11个法国神经介入中心的所有患者的数据进行了前瞻性收集和回顾性分析。分析治疗期间和治疗后发生的并发症以及1个月时的发病率和死亡率。结果：83例患者共85个动脉瘤被纳入本研究。77例患者的79个动脉瘤（92.9%）实现了技术成功。在9例患者（10.8%）中观察到围手术期并发症，导致3例患者（3.9%）出现永久性神经功能缺损。1个月时的发病率和死亡率分别为1.3%和0.0%。在治疗后3-24个月（平均5.3个月）对65/79个动脉瘤（82.3%）进行了血管造影随访。在37/65个动脉瘤（56.9%）中观察到动脉瘤完全闭塞;在23/65个（35.4%）中观察到瘤颈残留;在5/65个（7.7%）中观察到动脉瘤残留。结论：在这个大型前瞻性患者系列中，WEB血流中断是一种安全有效的技术。
BACKGROUND AND PURPOSE: The safety and efficacy of WEB flow disruption have been analyzed in small, retrospective series. The object of this study was to evaluate the safety and efficacy of WEB flow disruption in a large, multicenter, prospectively collected population.MATERIALS AND METHODS: Data from all patients treated with the WEB-DL device between June 2011 and October 2013 in 11 French neurointerventional centers were prospectively collected and retrospectively analyzed. Complications occurring during and after treatment were analyzed as well as morbidity and mortality at 1 month. Aneurysm occlusion status at the last follow-up was analyzed.RESULTS: Eighty-three patients with 85 aneurysms were included in this series. Technical success was achieved in 77 patients with 79 aneurysms (92.9%). Periprocedural complications were observed in 9 patients (10.8%), leading to permanent neurologic deficits in 3 (3.9%). Morbidity and mortality at 1 month were 1.3% and 0.0%, respectively. Angiographic follow-up was performed for 65/79 aneurysms (82.3%) 3-24 months after treatment (mean, 5.3 months). Complete aneurysm occlusion was observed in 37/65 aneurysms (56.9%); neck remnant, in 23/65 (35.4%); and aneurysm remnant, in 5/65 (7.7%).CONCLUSIONS: In this large prospective series of patients, WEB flow disruption was a safe and efficient technique.