Periodontal changes in children and adolescents with diabetes
Periodontal changes in children and adolescents with diabetes
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DOI：
10.2337/diacare.29.02.06.dc05-1355
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发表时间：
2006-02-01
期刊：
影响因子：
16.2
通讯作者：
Lamster, IB
中科院分区：
文献类型：
--
作者：
Lalla, E;Cheng, B;Lamster, IB
OBJECTIVE - To evaluate level of oral disease in children and adolescents with diabetesRESEARCH DESIGN AND METHODS - Dental caries and牙周病进行了临床评估，在182名儿童和青少年（6-18岁）糖尿病和160名非糖尿病对照subjects.RESULTS - There are no differences between cases and control subjects with respect to dental caries.与对照组相比，糖尿病儿童的牙菌斑和牙龈炎症水平显著较高。糖尿病儿童中有附着丧失证据（牙周病的标志）的牙齿数量明显更多（5.79 +/- 5.34 vs.对照组1.53 +/- 3.05，未校正P < 0.001）。当控制年龄、性别、种族、牙龈出血和牙科就诊频率时，糖尿病仍然是牙周炎的高度显著相关性，特别是在12至18岁的亚组中。在病例组中，BMI与结缔组织附着和骨骼的破坏显着相关，但糖尿病持续时间和平均HbA（lc）则不相关。结论-我们的研究结果表明，糖尿病患者的牙周破坏可以在生命的早期就开始，并且随着儿童成长为青少年而变得更加突出。应向年轻糖尿病患者提供旨在促进牙周病预防和治疗的计划。
OBJECTIVE - To evaluate the level of oral disease in children and adolescents with diabetesRESEARCH DESIGN AND METHODS - Dental caries and periodontal disease were clinically assessed in 182 children and adolescents (6-18 years of age) with diabetes and 160 nondiabetic control subjects.RESULTS - There were no differences between case and control subjects with respect to dental caries. Children with diabetes had significantly higher plaque and gingival inflammation levels compared with control subjects. The number of teeth with evidence of attachment loss (the hallmark of periodontal disease) was significantly greater in children with diabetes (5.79 +/- 5.34 vs. 1.53 +/- 3.05 in control subjects, unadjusted P < 0.001). When controlling for age, sex, ethnicity, gingival bleeding, and frequency of dental visits, diabetes remained a highly significant correlate of periodontitis, especially in the 12- to 18-year-old subgroup. in the case group, BMI was significantly correlated with destruction of connective tissue attachment and bone, but duration of diabetes and mean HbA(lc) were not.CONCLUSIONS - Our findings suggest that periodontal destruction can start very early in life in diabetes and becomes more prominent as children become adolescents. Programs designed to promote periodontal disease prevention and treatment should be provided to young patients with diabetes.