Effect of the fetal placenta and of a rabbit pituitary extract on plasma progesterone in fetectomized rabbits.
Effect of the fetal placenta and of a rabbit pituitary extract on plasma progesterone in fetectomized rabbits.
复制标题
胎儿胎盘和兔垂体提取物对去胎兔血浆孕酮的影响。
DOI：
--
复制
发表时间：
1979
期刊：
影响因子：
--
通讯作者：
R. Thau
中科院分区：
文献类型：
--
作者：
J. Lanman;R. Thau
当正常妊娠兔在第18天切除胎儿和胎盘时，血浆孕酮水平在48小时内迅速下降到非妊娠值。如果只切除胎儿，保留胎盘，这种下降在很大程度上可以防止，但当胎盘的胎儿成分也被切除时，这种下降就不会发生。这些结果表明卵巢黄体酮的产生依赖于胎盘胎儿部分产生的营养影响。兔垂体提取物在去除胎儿和胎盘后至少72小时内维持卵巢黄体酮的产生。
When fetuses and placentas were removed on Day 18 in normal pregnant rabbits, plasma progesterone levels declined rapidly to non-pregnant values within 48 h. This decline was largely prevented if only fetectomy was performed, leaving the placentas in situ, but not when the fetal components of the placentas were also removed. These results suggested that ovarian progesterone production was dependent upon trophic influences emanating from the fetal portions of the placentas. Ovarian progesterone production was maintained by an extract of rabbit pituitaries for at least 72 h after removal of fetuses and placentas.