Cholelithiasis in sickle cell anemia: surgical or medical management.
Cholelithiasis in sickle cell anemia: surgical or medical management.
复制标题
镰状细胞贫血症中的胆石症：手术或药物治疗。
DOI：
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发表时间：
1980
期刊：
影响因子：
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通讯作者：
R. Scott
中科院分区：
文献类型：
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作者：
C. Stephens;R. Scott
·在急诊室接受治疗的100名镰状细胞性贫血患者中，有40名被诊断为胆石症。网织红细胞增多症的发病率与性别或程度无关，但随年龄增长而增加，血红蛋白F百分比较低和血红蛋白病并发症较多的患者发病率可能更高。胆石症在11岁以下的儿童中并不罕见。在29例择期胆囊切除术中未发现重大手术并发症，但7例患者因真实的或疑似急性胆囊炎而进行的紧急胆囊切除术导致多个重大术后问题。由于择期手术的发病率较低，以及随后腹痛危象处理的简化，建议对稳定的镰状细胞病患者进行择期胆囊切除术。镰状细胞危象或急性胆囊炎时应避免手术，因为手术会增加发病率。（《内科学文献》140：648-651，1980）
• Cholelithiasis was diagnosed in 40 of 100 consecutive patients with sickle cell anemia treated in the emergency room. Incidence apparently was not related to sex or degree of reticulocytosis, but did increase with age and perhaps was greater in patients with lower percentage of hemoglobin F and more complications of their hemoglobinopathy. Cholelithiasis was not unusual in children less than 11 years old. No major surgical complications were noted during 29 elective cholecystectomies, but urgent cholecystectomy, performed for real or suspected acute cholecystitis in seven patients, resulted in multiple major postoperative problems. With the low morbidity of elective procedures, as well as simplification of subsequent abdominal pain crisis management, elective cholecystectomy in patients with stable sickle cell conditions is recommended. Surgery during sickle cell crises or acute cholecystitis, with the attendant increased morbidity, should be avoided. ( Arch Intern Med 140:648-651, 1980)