Risk factors for patients developing a fulminant course with acute myocarditis

Risk factors for patients developing a fulminant course with acute myocarditis
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DOI:
10.1253/circj.68.734
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发表时间:
2004-08-01
影响因子:
3.3
通讯作者:
Hishida, H
Hishida, H
中科院分区:
医学3区
文献类型:
--
作者:
Kato, S;Morimoto, S;Hishida, H

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背景:急性心肌炎发病时的暴发性病程很难预测,因此本研究的目的是确定可预测的临床症状/体征或实验室结果。方法与结果对39例急性淋巴细胞性心肌炎患者进行分析,其中8例入院时表现为休克。暴雷组定义为入院后发生休克,需要主动脉内球囊泵送或经皮心肺支持的12例患者,非暴雷组包括27例无休克的患者。比较两组患者入院时各项参数,并进行多元logistic回归分析,剔除6例部分缺失值患者。在暴发性组,c反应蛋白(7.0+/-7.0 vs 2.3+/-2.2 mg/dl, p
Background A fulminant course can be difficult to predict at the onset of acute myocarditis, so the aim of the present study was to identify the predictive clinical symptoms/signs or laboratory findings.Methods and Results Thirty-nine patients with acute lymphocytic myocarditis, excluding 8 who manifested shock at admission, were studied. The fulminant group was defined as 12 patients who developed shock after admission, requiring intraaortic balloon pumping or percutaneous cardiopulmonary support, and the non-fulminant group comprised the 27 patients without shock. Various parameters at admission were compared between the 2 groups, together with multiple logistic regression analysis, excluding 6 patients with partially missing values. In the fulminant group, C-reactive protein (7.0+/-7.0 vs 2.3+/-2.2 mg/dl, p