The visual analogue pain intensity scale: what is moderate pain in millimetres?
The visual analogue pain intensity scale: what is moderate pain in millimetres?
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DOI：
10.1016/s0304-3959(97)00005-5
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发表时间：
1997-08-01
期刊：
影响因子：
7.4
通讯作者：
McQuay, HJ
中科院分区：
文献类型：
--
作者：
Collins, SL;Moore, RA;McQuay, HJ
确保镇痛药试验具有足够敏感性的一种方法是对已确定中度至重度疼痛的患者进行干预试验。通常的标准是在分类疼痛强度量表上至少有中度疼痛。当视觉模拟量表（VAS）是试验中唯一的疼痛指标时，我们需要知道VAS上的哪一点代表中度疼痛，以便当基线疼痛强度至少为中度时，这些试验可以纳入荟萃分析。为了研究这一点，我们使用了1080例患者的个体数据，这些患者来自各种镇痛药的随机对照试验。在相同条件下，使用4分分类疼痛强度量表和疼痛强度VAS测量基线疼痛。检查了736例报告中度疼痛的患者和344例报告重度疼痛的患者的VAS评分分布。还按性别检查了中度或重度疼痛对应的VAS评分。报告中度疼痛的患者记录的基线VAS评分与报告重度疼痛的患者显著不同。在报告中度疼痛的患者中，85%的患者在相应的VAS评分超过30 mm，平均评分为49 mm。对于报告重度疼痛的患者，85%的患者评分超过54 mm，平均评分为75 mm。男性和女性相应的VAS评分之间没有差异。我们的研究结果表明，如果患者记录的基线VAS评分超过30 mm，则在4分制分类量表上可能至少记录了中度疼痛。(C)1997年国际疼痛研究协会。出版社：Elsevier Science B.V.
One way to ensure adequate sensitivity for analgesic trials is to test the intervention on patients who have established pain of moderate to severe intensity. The usual criterion is at least moderate pain on a categorical pain intensity scale. When visual analogue scales (VAS) are the only pain measure in trials we need to know what point on a VAS represents moderate pain, so that these trials can be included in metaanalysis when baseline pain of at least moderate intensity is an inclusion criterion. To investigate this we used individual patient data from 1080 patients from randomised controlled trials of various analgesics. Baseline pain was measured using a 4-point categorical pain intensity scale and a pain intensity VAS under identical conditions. The distribution of the VAS scores was examined for 736 patients reporting moderate pain and for 344 reporting severe pain. The VAS scores corresponding to moderate or severe pain were also examined by gender. Baseline VAS scores recorded by patients reporting moderate pain were significantly different from those of patients reporting severe pain. Of the patients reporting moderate pain 85% scored over 30 mm on the corresponding VAS, with a mean score of 49 mm. For those reporting severe pain 85% scored over 54 mm with a mean score of 75 mm. There was no difference between the corresponding VAS scores of men and women. Our results indicate that if a patient records a baseline VAS score in excess of 30 mm they would probably have recorded at least moderate pain on a 4-point categorical scale. (C) 1997 International Association for the Study of Pain. Published by Elsevier Science B.V.