Mouth opening and trismus in patients undergoing curative treatment for head and neck cancer

Mouth opening and trismus in patients undergoing curative treatment for head and neck cancer
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DOI:
10.1016/j.ijom.2014.12.009
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发表时间:
2015-03-01
影响因子:
2.4
通讯作者:
Tan, S. T.
Tan, S. T.
中科院分区:
医学3区
文献类型:
--
作者:
Steiner, F.;Evans, J.;Tan, S. T.

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这项研究记录了嘴巴张开和三叉眼的发生率和致病因素(治疗完成后6个月)。患者对张嘴对生活质量的影响从0(无影响)到10(最大影响)进行评分。120例患者平均张口度为40.1 mm(11~65 mm),其中34例(28.3%)出现张口不张。手术和放射治疗、手术和放化疗、切除和重建与张口度降低有关。张口对三叉神经症患者和无三叉神经症患者的生活质量的平均影响分别为3.8和1.5。接受放化疗或综合手术加放射治疗的患者对生活质量的平均影响有显著差异(分别为4.0比1.0,3.6比1.6)。三叉神经症对患者的生活质量有负面影响。多模式治疗会降低张口度,增加三叉神经症的发生率,降低生活质量。
This study documents mouth opening and the incidence of and factors contributing to trismus (6 months after treatment completion. Patients rated the impact of mouth opening on quality of life from 0 (no effect) to 10 (greatest effect). The mean mouth opening in 120 patients was 40.1 mm (range 11-65 mm), with trismus occurring in 34 (28.3%) patients. Surgery and radiotherapy, surgery and chemoradiotherapy, and resection and reconstruction were associated with reduced mouth opening. The mean effect of mouth opening on quality of life for those with and without trismus was 3.8 and 1.5, respectively. There was a significant difference between the mean effect on quality of life for patients with and without trismus for those patients who underwent chemoradiotherapy or combined surgery and radiotherapy (4.0 vs. 1.0, and 3.6 vs. 1.6 respectively). Trismus impacts negatively on patient quality of life. Multi-modality treatment is associated with decreased mouth opening, an increased: incidence of trismus, and reduced quality of life.