Placental type of membrane-bound arylamidase (Shiba isoenzyme) found in human cancerous lung
Placental type of membrane-bound arylamidase (Shiba isoenzyme) found in human cancerous lung
复制标题
在人类癌性肺癌中发现胎盘型膜结合芳基酰胺酶（柴犬同工酶）
DOI：
10.1016/0009-8981(79)90251-1
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发表时间：
1979
影响因子：
5
通讯作者：
K. Tatsuo
中科院分区：
文献类型：
--
作者：
H. Kunio;Yokoyama Masako;K. Tatsuo
在肺腺癌组织中发现一种胎盘型膜结合芳酰胺酶（Shiba同工酶）。癌性肺膜结合芳基酰胺酶具有相同的电泳迁移率，等电点（pH 4.2），和敏感性的SDS灭活胎盘膜结合芳基酰胺酶。癌肺膜结合的芳基酰胺酶的分子量和动力学性质类似于正常肺膜结合的芳基酰胺酶，但不同的正常肺膜结合的芳基酰胺酶的电泳迁移率，等电点，热稳定性和SDS灭活。
A placental type of membrane-bound arylamidase (Shiba isoenzyme) was found in the tissue of adenocarcinoma of the lung. Cancerous lung membranebound arylamidase had the same electrophoretic mobility, isoelectric point (pH 4.2), and susceptibility to SDS inactivation as placental membrane-bound arylamidase. Cancerous lung membrane-bound arylamidase had molecular weight and kinetic properties similar to normal lung membrane-bound arylamidase, but differed from the normal lung membrane-bound arylamidase with respect to electrophoretic mobility, isoelectric point, heat stability and inactivation by SDS.