Transient epileptic amnesia: Update on a slowly emerging epileptic syndrome
Transient epileptic amnesia: Update on a slowly emerging epileptic syndrome
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DOI：
10.1016/j.neurol.2014.11.010
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发表时间：
2015-03-01
影响因子：
3
通讯作者：
Bartolomei, F.
中科院分区：
文献类型：
--
作者：
Felician, O.;Tramoni, E.;Bartolomei, F.
Transient epileptic amnesia (TEA) is a recently individualized, late-onset, pharmaco-sensitive form of mesial temporal lobe epilepsy with recurrent episodes of acute memory loss, but also interictal memory disturbances characterized by autobiographical and topographical memory impairment and a long-term consolidation deficit. In this article, we review the main clinical and electrophysiological characteristics of TEA, discuss its putative neuroanatomical substrate and mechanisms, common features and how it differs from related concepts, with the overall aim to defend the idea that TEA deserves to be recognized as a distinct epilepsy syndrome. While the pathophysiological basis remains largely unknown, emotional and/or dysimmune factors may have a potential influence. Most importantly, the concept of TEA is highly relevant to tertiary epilepsy and memory clinics, but also to routine neurology practice, leading to an adequate diagnosis and management of epilepsy-related, acute and long-standing memory deficits. (C) 2015 Elsevier Masson SAS. All rights reserved.
