Design of a handheld optical coherence microscopy endoscope.
Design of a handheld optical coherence microscopy endoscope.
复制标题
手持式光学相干显微镜内窥镜的设计。
DOI：
10.1117/1.3594149
复制
发表时间：
2011
影响因子：
3.5
通讯作者：
Barton,JenniferK
中科院分区：
文献类型：
--
作者：
Korde,VrushaliR;Liebmann,Erica;Barton,JenniferK
Optical coherence microscopy (OCM) combines coherence gating, high numerical aperture optics, and a fiber-core pinhole to provide high axial and lateral resolution with relatively large depth of imaging. We present a handheld rigid OCM endoscope designed for small animal surgical imaging, with a 6-mm diam tip, 1-mm scan width, and 1-mm imaging depth.X-Yscanning is performed distally with mirrors mounted to micro galvonometer scanners incorporated into the endoscope handle. The endoscope optical design consists of scanning doublets, an afocal Hopkins relay lens system, a 0.4 numerical aperture water immersion objective, and a cover glass. This endoscope can resolve laterally a 1.4-μm line pair feature and has an axial resolution (full width half maximum) of 5.4 μm. Images taken with this endoscope of freshex-vivomouse ovaries show structural features, such ascorpus luteum, primary follicles, growing follicles, and fallopian tubes. This rigid handheld OCM endoscope can be useful for a variety of minimally invasive and surgical imaging applications.
