FLOW-INDEPENDENT VISCOELASTIC PROPERTIES OF ARTICULAR-CARTILAGE MATRIX
FLOW-INDEPENDENT VISCOELASTIC PROPERTIES OF ARTICULAR-CARTILAGE MATRIX
复制标题
DOI：
10.1016/0021-9290(78)90075-1
复制
发表时间：
1978-01-01
影响因子：
2.4
通讯作者：
BODINE, AJ
中科院分区：
文献类型：
--
作者：
HAYES, WC;BODINE, AJ
Miles开发的正弦剪切发生器用于测量牛关节软骨的粘弹性复合剪切模量。剪切加载模式将基质性质的测量与间隙流体的流动分离开来，并提供了对基质成分的生化变化高度敏感的与流动无关的测量。交联增加导致基质储存模量显著增加，而蛋白聚糖耗竭和胶原酶消化导致基质储存模量显著降低。在蛋白聚糖消耗组和胶原酶消化组之间也观察到复杂剪切模量的显著差异。
A sinusoidal shear generator developed by Miles is used to measure viscoelastic complex shear moduli for bovine articular cartilage. The shear loading mode uncouples the measurement of matrix properties from the flow of interstitial fluid and provides flow-independent measurements which are highly sensitive to biochemical alteration of the matrix constituents. Increased cross-linking causes significant increases in the matrix storage modulus while proteoglycan depletion and collagenase digestion cause significant decreases. Highly significant differences in complex shear moduli are also observed between the proteoglycan depletion group and the collagenase digestion group.