Using Participant Data to Extend the Evidence Base for Intensive Behavioral Intervention for Children With Autism
Using Participant Data to Extend the Evidence Base for Intensive Behavioral Intervention for Children With Autism
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DOI：
10.1352/1944-7558-115.5.381
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发表时间：
2010-09-01
影响因子：
2.1
通讯作者：
Cross, Scott
中科院分区：
文献类型：
--
作者：
Eldevik, Sigmund;Hastings, Richard P.;Cross, Scott
我们收集了16组自闭症儿童行为干预研究的个体参与者数据。在这些研究中，309名儿童接受了行为干预，39名接受了比较干预，105名为对照组。接受行为干预的儿童中，更多的儿童实现了可靠的智商变化（29.8%），而对照组和对照组分别为2.6%和8.7%，适应行为的可靠变化分别为20.6%和5.7%。这些结果相当于需要治疗5个IQ和7个适应行为，绝对风险分别降低23%和16%。在行为干预样本中，摄入时的智商和适应行为预测了适应行为的增益。干预的强度预示着智商和适应行为的提高。
We gathered individual participant data from 16 group design studies on behavioral intervention for children with autism. In these studies, 309 children received behavioral intervention, 39 received comparison interventions, and 105 were in a control group. More children who underwent behavioral intervention achieved reliable change in IQ(29.8%) compared with 2.6% and 8.7% for comparison and control groups, respectively, and reliable change in adaptive behavior was achieved for 20.6% versus 5.7% and 5.1%, respectively. These results equated to a number needed to treat of 5 for IQ and 7 for adaptive behavior and absolute risk reduction of 23% and 16%, respectively. Within the behavioral intervention sample, IQ and adaptive behavior at intake predicted gains in adaptive behavior. Intensity of intervention predicted gains in both IQ and adaptive behavior.