Histamine receptor signaling in energy homeostasis.
Histamine receptor signaling in energy homeostasis.
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DOI：
10.1016/j.neuropharm.2015.04.011
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发表时间：
2016-07
影响因子：
4.7
通讯作者：
Tabarean IV
中科院分区：
文献类型：
--
作者：
Tabarean IV
Histamine modulates several aspects of energy homeostasis. By activating histamine receptors in the hypothalamus the bioamine influences thermoregulation, its circadian rhythm, energy expenditure and feeding. These actions are brought about by activation of different histamine receptors and/or the recruitment of distinct neural pathways. In this review we describe the signaling mechanisms activated by histamine in the hypothalamus, the evidence for its role in modulating energy homeostasis as well as recent advances in the understanding of the cellular and neural network mechanisms involved.
