The role of RNA stability during bacterial stress responses and starvation.
The role of RNA stability during bacterial stress responses and starvation.
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DOI：
10.1046/j.1462-2920.2000.00119.x
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发表时间：
2000-08
影响因子：
5.1
通讯作者：
Kathy Takayama;Staffan Kjelleberg
中科院分区：
文献类型：
--
作者：
Kathy Takayama;Staffan Kjelleberg
细菌在自然环境的变化中引起快速和有效的协调适应方案。这些反应的特征是基因表达、生理学和形态学的巨大变化，这些变化对生物体的生存和随后的复制至关重要。对各种细菌的饥饿和应激反应的研究揭示了控制特定基因的表达和/或抑制的关键调控途径，这些基因最终促进分化和非分化生物体适应不利的生长条件。
Bacteria elicit rapid and efficiently orchestrated programmes of adaptation in response to changes in their natural environment. These responses are characterized by dramatic changes in gene expression, physiology and morphology that are paramount for the organism’s survival and, subsequently, replication. Studies of starvation and stress responses in various bacteria have shed light upon key regulatory pathways controlling the expression and/or repression of specific genes that ultimately facilitate adaptation to unfavourable growth conditions for both differentiating and non-differentiating organisms.