The neuropsychology of mood disorders.

The neuropsychology of mood disorders.
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DOI:
10.1007/s11920-006-0051-x
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发表时间:
2006-12-01
影响因子:
6.7
通讯作者:
Sahakian, Barbara J
Sahakian, Barbara J
中科院分区:
医学2区
文献类型:
--
作者:
Chamberlain, Samuel R;Sahakian, Barbara J

文献摘要

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认知功能障碍是我们理解情绪障碍的核心,包括患者经历、精神障碍诊断与统计手册标准和心理模型。在这篇文章中,我们重点介绍了使用神经心理学测试和功能神经成像技术来探索抑郁症和躁狂患者认知功能障碍的研究结果。我们特别关注情感加工偏差、对负面反馈的异常反应和决策。结果在当前概念的背景下讨论功能障碍的神经回路,并在重要的临床研究意义。
Cognitive dysfunction is central to our understanding of mood disorders in terms of patient experiences, Diagnostic and Statistical Manual of Mental Disorders criteria, and psychological models. In this article, we highlight key findings from studies that have used neuropsychological tests and functional neuroimaging techniques to explore cognitive dysfunction in patients with depression and mania. In particular, we focus on affective processing bias, abnormal response to negative feedback, and decision making. Results are discussed in the context of current conceptualizations of dysfunctional neural circuitry, and in relation to important clinical research implications.