MRI features of pigmented villonodular synovitis (PVNS)

MRI features of pigmented villonodular synovitis (PVNS)
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DOI:
10.1007/s10067-003-0827-x
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发表时间:
2004-02-01
影响因子:
3.4
通讯作者:
Qu, H
Qu, H
中科院分区:
医学3区
文献类型:
--
作者:
Cheng, XG;You, YH;Qu, H

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本研究的目的是描述PVNS的磁共振成像(MRI)特征。回顾性分析23例经手术病理证实的PVNS的X线及MR表现,重点分析其MR表现。男9例,女14例,平均年龄36岁。23例中,髋关节9例,膝关节8例,踝关节3例,手肘关节2例,腕关节1例。典型的MRI表现包括不同程度的结节性滑膜增生,从轻度增生到广泛肿块,所有病例均出现关节积液,15例出现多发性骨侵蚀。由于关节间隙狭窄,骨受累常见于髋、踝、肘和腕。虽然膝关节有一个松散的关节囊,骨受累是罕见的。含铁血黄素是一种磁性物质,其存款在增生性滑膜组织上导致在T1和T2加权像上增生性滑膜肿块内出现斑点状低信号或广泛的低信号区,最好在快速场回波(FFE)序列MRI图像上看到。脂肪抑制序列掩盖了存款。这是PVNS的诊断。PVNS的MRI特征包括不同程度的滑膜增生、关节积液和骨质侵蚀,特别是滑膜肿块内含铁血黄素的存款。含铁血黄素存款,在FFE序列上表现为低信号区,可诊断PVNS。
The aim of this study was to characterize the magnetic resonance imaging (MRI) features of PVNS. The radiographs and MR images of 23 pathologically proven cases of PVNS were retrospectively reviewed, with emphasis on MR images. There were 9 males and 14 females, mean age 36 years. Of 23 cases, 9 occurred in the hip, 8 in the knee, 3 in the ankle, 2 in the elbow and 1 in the wrist. Typical MRI findings included variable extent of nodular synovial proliferation, from mild proliferation to extensive masses, joint effusion in all cases, and multiple bony erosions in 15. Owing to the tight joint space, bone involvement was frequently seen in the hip, ankle, elbow and wrist. Although the knee joint had a loose capsule, bone involvement was rarely seen. Hemosiderin is a magnetic material, its deposit on proliferative synovial tissue resulting in a spotty low signal or extensive low signal area within the proliferative synovial masses on T-1- (T1WI) and T-2-weighted (T2WI) images, best seen on fast field echo (FFE) sequence MRI images. Fat-suppressed sequences obscured the deposit . This is diagnostic of PVNS. The MRI features of PVNS include variable extent of synovial proliferation, joint effusion and erosion of bone, and in particular the deposit of hemosiderin within the synovial masses. The deposit of hemosiderin, appearing as a low signal area best seen on FFE sequence, is diagnostic for PVNS.