HPLC of Morphine with Electrochemical Detection: Analysis in Human Plasma

HPLC of Morphine with Electrochemical Detection: Analysis in Human Plasma
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吗啡的 HPLC 与电化学检测:人血浆中的分析

DOI:
10.1177/000456328402100209
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发表时间:
1984
影响因子:
2.2
通讯作者:
R. Bullingham
R. Bullingham
中科院分区:
医学4区
文献类型:
--
作者:
R. Moore;D. Baldwin;H. McQuay;R. Bullingham

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A method is described for the measurement of morphine in human plasma by ion-paired reverse-phase liquid chromatography. It includes a novel solid-phase extraction of morphine from plasma which is simple, rapid and complete. No known morphine metabolites could be shown to interfere with the measurements. Determination of morphine pharmacokinetics in patients undergoing heart surgery with 1 mg/kg intravenous morphine produced plasma morphine clearances which agreed with established estimates.
血浆和脑脊液提取前后吗啡放射免疫测定的特异性。
DOI: 10.1002/jps.2600720107
发表时间: 1983
影响因子: 3.8
作者:
Grabinski,PY;Kaiko,RF;Walsh,TD;Foley,KM;Houde,RW
通讯作者: Houde,RW