A review of the interactions between multiple insecticide resistance loci
A review of the interactions between multiple insecticide resistance loci
复制标题
DOI：
10.1016/j.pestbp.2009.07.010
复制
发表时间：
2010-06-01
影响因子：
4.7
通讯作者：
Scott, Jeffrey G.
中科院分区：
文献类型：
--
作者：
Hardstone, Melissa C.;Scott, Jeffrey G.
在许多害虫种群中，杀虫剂抗药性是一个日益严重的世界性问题，许多抗药性案例是多基因的。因此，重要的是调查杀虫剂抗性基因座之间发生的相互作用的类型，因为这将决定抗性水平(以及化学防治策略的有效性)。相互作用也在田间多基因抗性的进化和/或维持中发挥作用。鉴于有限数量的机制会产生抵抗力，有可能为机制之间的相互作用制定一般规则。有几个变量可能决定相互作用的类型，如抗性机制的性质、基因型等。相互作用可以是协同的、拮抗的或相加的。基于此文献综述，当多个纯合子抗性基因座为杂合子时，最常见的相互作用是协同作用和相加作用。当一个基因座是纯合子而另一个基因座是杂合子时，最常见的相互作用是协同作用，尽管很少有研究检验这种类型的相互作用。讨论了驱动这些相互作用的可能因素、趋势的例外情况以及未来的研究需求。(C)2009 Elsevier Inc.保留所有权利。
Insecticide resistance is an ever escalating problem worldwide in many pest populations and numerous cases of insecticide resistance are polygenic. Therefore, it is important to investigate the types of interactions that occur between insecticide resistance loci as this will dictate the level of resistance (and effectiveness of a chemical control strategy). Interactions also play a role in the evolution and/or maintenance of multigenic resistance in the field. Given that a limited number of mechanisms confer resistance, it might be possible to establish general rules for interactions between mechanisms. Several variables might dictate the type of interaction, such as the nature of the resistance mechanisms, genotype, etc. Interactions can be synergistic, antagonistic or additive. Based on this literature review, the most common interaction of multiple homozygous resistance loci is synergistic and additive when loci are heterozygous. When one locus is homozygous and the other locus is heterozygous the most common interaction was synergistic, although very few studies have examined this type of interaction. Possible factors that drive these interactions, exceptions to the trends, and future research needs are discussed. (C) 2009 Elsevier Inc. All rights reserved.