Bioaccumulation behavior and spatiotemporal trends of per- and polyfluoroalkyl substances in Indo-Pacific humpback dolphins from the Pearl River Estuary, China.
Bioaccumulation behavior and spatiotemporal trends of per- and polyfluoroalkyl substances in Indo-Pacific humpback dolphins from the Pearl River Estuary, China.
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DOI：
10.1016/j.scitotenv.2018.12.278
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发表时间：
2019-03
期刊：
影响因子：
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通讯作者：
D. Gui;Mei Zhang;Tao Zhang;Bo Zhang;Wenzhi Lin;Xian Sun;Xinjian Yu;Wen Liu;Yuping Wu
中科院分区：
文献类型：
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作者：
D. Gui;Mei Zhang;Tao Zhang;Bo Zhang;Wenzhi Lin;Xian Sun;Xinjian Yu;Wen Liu;Yuping Wu
于2004年至2016年在中国珠江口（PRE）搁浅的中华白海豚（Sousa chinensis）的肝脏（n= 52）和肾脏（n= 18）组织中测定了十六氟烷基和多氟烷基物质（PFAS）。肝脏样本中全氟辛烷磺酸（PFOS）、全氟辛酸（PFOA）和大多数其他全氟辛烷磺酸的平均浓度分别高于全球鲸类动物中先前报告的任何记录。46%的海豚肝脏样本中的全氟辛烷磺酸水平超过了鲸目动物的肝毒性阈值。我们首次发现，随着碳链长度（C5-C16）的增加，全氟羧酸（PFCAs）在肝脏和肾脏之间的分布模式呈U形趋势，而全氟烷烃磺酸（PFASs）则呈下降趋势（C4-C10），这可以通过PFAS类似物与蛋白质的结合效率来解释。在伶仃洋，经年龄校正后，总PFASs浓度最高的海豚聚集在河口附近，这与PFASs在环境中的空间分布相一致。观察到许多PFAS的显著时间趋势。全氟辛酸、全氟壬酸（PFNA）、全氟癸酸（PFDA）和全氟庚酸（PFHpA）的浓度均在2011年达到峰值，随后呈下降趋势，而全氟十一烷酸（PFUdA）和全氟癸烷磺酸盐（PFDS）则呈持续下降趋势。本研究结果有助于了解PFASs在PRE海豚体内的组织分布和时空变化趋势，对了解PFASs暴露风险及其在华南地区的工业排放具有重要意义。
Sixteenper- and polyfluoroalkyl substances (PFASs) were measured in liver (n= 52) and kidney (n= 18) tissues of Indo-Pacific humpback dolphins (Sousa chinensis) stranded in the Pearl River Estuary (PRE) of China between 2004 and 2016. The average concentrations of perfluorooctane sulfonate (PFOS), perfluorooctanoic acid (PFOA) and most of other PFASs in the liver samples were respectively greater than any records previously reported in cetaceans globally. PFOS levels in 46% of dolphin liver samples exceeded the hepatic toxicity threshold in cetaceans. For the first time, we found a U-shaped trend for the distribution pattern of perfluorinated carboxylic acids (PFCAs) between liver and kidney with increasing carbon chain lengths (C5-C16), whereas a descending trend (C4-C10) was found for perfluoroalkane sulfonic acids (PFASs), which may be explained by binding efficiencies of PFAS analogues to proteins. Dolphins with the highest levels of ∑PFASs (age-corrected) were clustered near the river outlets in Lingdingyang area, which agrees with the spatial distribution of PFASs in the environment. Significant temporal trends were observed for many PFASs. Concentrations of PFOA, perfluorononanoic acid (PFNA), perfluorodecanoic acid (PFDA) and perfluoroheptanoic acid (PFHpA) all peaked in year 2011, followed by a decreasing trend, while a consistently descending trend was shown for perfluoroundecanoic acid (PFUdA) and perfluorodecane sulfonate (PFDS). Our findings contribute to the knowledge of tissue distribution and spatiotemporal trends of PFASs in the PRE dolphins, which are valuable for us to understand the PFASs exposure risk and their industrial emission in Southern China.