Phytochemical compositions and biological activities of the branches and leaves of Ormosia hosiei Hemsl. et Wils.
Phytochemical compositions and biological activities of the branches and leaves of Ormosia hosiei Hemsl. et Wils.
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DOI：
10.1016/j.jpba.2023.115238
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发表时间：
2023-01
影响因子：
3.4
通讯作者：
Yifan Lin;Shaohua Li;Tao Chen;Yan-hua Lin;Zai-xing Cheng;Lin Ni;Jin-jian Lu;Ming-Qing Huang
中科院分区：
文献类型：
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作者：
Yifan Lin;Shaohua Li;Tao Chen;Yan-hua Lin;Zai-xing Cheng;Lin Ni;Jin-jian Lu;Ming-Qing Huang
红豆et Wils.是一种经济和药用植物，越来越多地在中国栽培，然而，其枝叶经常被修剪为废物。本研究首次从植物化学角度研究了O. hosiei。采用UPLC-MS/MS技术鉴定了37个特征化合物，其中12个为首次在O. hosiei。27种酚类化合物进一步定量分析表明，不同叶龄的叶和枝中酚类化合物含量存在显著差异。观察到了hosei。该提取物具有较好的抗氧化、抗α-葡萄糖苷酶、抗酪氨酸酶和抗神经炎症作用，其生物活性与总酚含量和12种单体酚含量显著相关。柚苷、染料木黄酮、牡荆素、牡荆素-2-O-鼠李糖苷、黄荆树脂醇和黄荆树脂醇-4-O-β-D-葡萄糖苷可作为O. hosiei。我们的研究结果提供了坚实的证据，分支和叶ofO。hosiei值得更多的关注和开发，考虑到其作为功能性食品或草药的潜力。
Ormosia hosieiHemsl. et Wils. is an economical and medicinal plant, increasingly cultivated in China; however, its branches and leaves are often pruned as waste. This is the first study focused on the phytochemical profiles and antioxidant, anti-α-glucosidase, anti-tyrosinase, and anti-neuroinflammatory activities of the branches and leaves ofO. hosiei. Herein, thirty-seven characteristic compounds were identified by UPLC-MS/MS and twelve were detected for the first time inO. hosiei. Twenty-seven phenolics were further quantified and significant differences in phenolic compositions between the branches and leaves ofO. hosieiwere observed. The ethanol extracts exhibited promising antioxidant, anti-α-glucosidase, anti-tyrosinase, and anti-neuroinflammatory effects, and the bioactivities significantly correlated with total phenolic content and twelve individual phenolics. Naringin, genistein, vitexin, vitexin-2-O-rhamnoside, syringaresinol and syringaresinol-4-O-β-D-glucopyranoside can be considered potential quality markers ofO. hosiei. Our results provided solid evidence that the branches and leaves ofO. hosieideserve more attention and exploitation, considering the potential to be developed as functional foods or herbal medicines.