The 3′ cis-acting genomic replication element of the severe acute respiratory syndrome coronavirus can function in the murine coronavirus genome

The 3′ cis-acting genomic replication element of the severe acute respiratory syndrome coronavirus can function in the murine coronavirus genome
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DOI:
10.1128/jvi.78.14.7846-7851.2004
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发表时间:
2004-07-01
影响因子:
5.4
通讯作者:
Masters, PS
Masters, PS
中科院分区:
医学2区
文献类型:
--
作者:
Goebel, SJ;Taylor, J;Masters, PS

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严重急性呼吸综合征冠状病毒基因组的3‘非翻译区(3’UTR)可以在功能上替代原型2组冠状病毒小鼠肝炎病毒(MHV)中的相应区域。相反,具有代表性的第1组或第3组冠状病毒的3‘非编码区不能作为MHV 3’非编码区的替代品。
The 3' untranslated region (3' UTR) of the genome of the severe acute respiratory syndrome coronavirus can functionally replace its counterpart in the prototype group 2 coronavirus mouse hepatitis virus (MHV). By contrast, the 3' UTRs of representative group 1 or group 3 coronaviruses cannot operate as substitutes for the MHV 3' UTR.