Genotyping Natural Killer Immune Checkpoints to Discover Biomarkers of Response.
Genotyping Natural Killer Immune Checkpoints to Discover Biomarkers of Response.
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DOI：
10.1158/1078-0432.ccr-17-2884
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发表时间：
2018-01-01
期刊：
影响因子：
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通讯作者：
Hsu KC
中科院分区：
文献类型：
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作者：
Cheung NK;Hsu KC
Immune checkpoints have been a focus of immunotherapy in the recent decade. Killer-cell immunoglobulin-like receptors (KIR) and their cognate human leukocyte antigen (HLA) class I ligands have evolved as checkpoints to ensure self-tolerance of natural iiller (NK) cells. Both KIR and HLA genetic profiles are potential biomarkers of immunotherapy outcome.
